U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula H3N
Molecular Weight 16.0296
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIA N-13

SMILES

[13NH3]

InChI

InChIKey=QGZKDVFQNNGYKY-BJUDXGSMSA-N
InChI=1S/H3N/h1H3/i1-1

HIDE SMILES / InChI
[13N]Ammonia ([13N]NH3) is a useful 13N-labeled compound that has been developed as a positron emission tomography (PET) imaging agent for assessing regional blood flow in tissues. It is indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease. No adverse reactions have been reported for Ammonia N 13 Injection based on a review of the published literature, publicly available reference sources, and adverse drug reaction reporting systems. The possibility of interactions of Ammonia N 13 Injection with other drugs taken by patients undergoing PET imaging has not been studied.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
AMMONIA N 13

Approved Use

Ammonia N 13 Injection is a radioactive diagnostic agent for Positron Emission Tomography (PET) indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease.

Launch Date

2007

Sample Use Guides

Rest Imaging Study: • Aseptically withdraw Ammonia N 13 Injection from its container and administer 10-20 mCi (0.368 – 0.736 GBq) as a bolus through a catheter inserted into a large peripheral vein. • Start imaging 3 minutes after the injection and acquire images for a total of 10-20 minutes. Stress Imaging Study: • If a rest imaging study is performed, begin the stress imaging study 40 minutes or more after the first Ammonia N13 injection to allow sufficient isotope decay. • Administer a pharmacologic stress-inducing drug in accordance with its labeling. • Aseptically withdraw Ammonia N 13 Injection from its container and administer 10-20 mCi (0.368 – 0.736 GBq) of Ammonia N 13 Injection as a bolus at 8 minutes after the administration of the pharmacologic stress-inducing drug. • Start imaging 3 minutes after the Ammonia N 13 Injection and acquire images for a total of 10-20 minutes.
Route of Administration: Intravenous
Name Type Language
AMMONIA N-13
ORANGE BOOK  
Common Name English
AMMONIA N-13 [ORANGE BOOK]
Common Name English
((SUP 13)N)AMMONIA
Common Name English
AMMONIA, N-13
ORANGE BOOK  
Common Name English
AMMONIA N 13 [USP IMPURITY]
Common Name English
AMMONIA (13N)
Common Name English
AMMONIA-(SUP 13)N
Common Name English
AMMONIA N 13 [USAN]
Common Name English
AMMONIA N 13
USAN   USP  
USAN  
Official Name English
Ammonia (13N) [WHO-DD]
Common Name English
AMMONIA, N-13 [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
NDF-RT N0000177914
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
NDF-RT N0000000205
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
NCI_THESAURUS C1446
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
Code System Code Type Description
DRUG BANK
DB09326
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
FDA UNII
9OQO0E343Z
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
NCI_THESAURUS
C79714
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
EVMPD
SUB11705MIG
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
RXCUI
1305558
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY RxNorm
DRUG CENTRAL
4472
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
DAILYMED
9OQO0E343Z
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
CHEBI
135980
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
USAN
BB-73
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
CAS
34819-78-8
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
WIKIPEDIA
Ammonia N-13
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
ChEMBL
CHEMBL1160819
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
LACTMED
Nitrogen-13
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
LACTMED
Ammonia N 13
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
EPA CompTox
DTXSID601027603
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY
PUBCHEM
119432
Created by admin on Fri Dec 15 17:19:55 GMT 2023 , Edited by admin on Fri Dec 15 17:19:55 GMT 2023
PRIMARY